Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349922 | 0.87 | MEN1 (0.43) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL22529957 | 0.87 | MEN1 (0.43) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL29352030 | 0.85 | AURKA (0.38) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL22529924 | 0.85 | AURKA (0.38) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL22529954 | 0.83 | HSPB1 (0.47) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL29351967 | 0.83 | HSPB1 (0.47) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL22530094 | 0.76 | KDM4E (0.43) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL29351821 | 0.76 | KDM4E (0.43) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL28937050 | 0.75 | ABL1 (0.41) | MEN1KMT2AKDM4EGRM5NPC1 | |
| SCHEMBL22530943 | 0.74 | MAPK8 (0.38) | MEN1KMT2AKDM4EGRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023079132-A1 | PHARMACEUTICAL COMBINATIONS FOR TREATING CANCER | CELLESTIA BIOTECH AG (CH) | 2023-05-11 | — | — | WO | disclosed |