Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670961 | 1.00 | BRD4 (0.49) | BRD4HDAC1HDAC6MMP1MMP3 | |
| SCHEMBL28707698 | 0.86 | MAPT (0.54) | BRD4MAPTALDH1A1LMNAFAAH | |
| SCHEMBL29670965 | 0.86 | BRD4 (0.50) | BRD4HDAC1HDAC6MMP1MMP3 | |
| SCHEMBL28705613 | 0.86 | BRD4 (0.50) | BRD4HDAC1HDAC6MMP1MMP3 | |
| SCHEMBL28715966 | 0.84 | ALDH1A1 (0.55) | MAPTALDH1A1LMNAFAAHCACNA1G | |
| SCHEMBL28719013 | 0.84 | BRD4 (0.48) | BRD4HDAC1HDAC6MAPTTRPV1 | |
| SCHEMBL31620916 | 0.84 | HDAC1 (0.62) | BRD4HDAC1HDAC6MMP1MMP3 | |
| SCHEMBL28707706 | 0.83 | ALDH1A1 (0.51) | BRD4MAPTTRPV1ALDH1A1FAAH | |
| SCHEMBL28718309 | 0.83 | BRD4 (0.47) | BRD4MAPTTRPV1ALDH1A1ACHE | |
| SCHEMBL29670959 | 0.83 | BRD4 (0.47) | BRD4HDAC1HDAC6MAPTTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |