Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718274 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTSIGMAR1MAPK1 | |
| SCHEMBL29670971 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTSIGMAR1MAPK1 | |
| SCHEMBL28718309 | 0.90 | BRD4 (0.47) | ALDH1A1KMT2AMAPTSIGMAR1BRD4 | |
| SCHEMBL28722559 | 0.88 | KDM4E (0.53) | ALDH1A1KMT2ASIGMAR1MAPK1BRD4 | |
| SCHEMBL28715966 | 0.87 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28707698 | 0.86 | MAPT (0.54) | ALDH1A1KMT2AMAPTPKMBRD4 | |
| SCHEMBL28707700 | 0.86 | GAA (0.48) | ALDH1A1KMT2AMAPTBRD4MEN1 | |
| SCHEMBL28705613 | 0.84 | BRD4 (0.50) | ALDH1A1MAPTBRD4TRPV1KDM4E | |
| SCHEMBL29670965 | 0.84 | BRD4 (0.50) | ALDH1A1MAPTBRD4TRPV1KDM4E | |
| SCHEMBL28937209 | 0.83 | BRD4 (0.49) | ALDH1A1MAPTBRD4TRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |