Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 10/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29452801 | 1.00 | JAK2 (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL28938265 | 1.00 | JAK2 (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL23041380 | 0.95 | MME (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL23041379 | 0.95 | MME (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL23042014 | 0.84 | ADORA3 (0.47) | ADORA3ADORA2A | |
| SCHEMBL28721845 | 0.83 | RIPK1 (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL29452821 | 0.83 | RIPK1 (0.36) | JAK2JAK1JAK3MDM2IDO1 | |
| SCHEMBL29452642 | 0.83 | PRKD1 (0.37) | JAK2JAK1JAK3IDO1RIPK1 | |
| SCHEMBL28724377 | 0.83 | PRKD1 (0.37) | JAK2JAK1JAK3IDO1RIPK1 | |
| SCHEMBL28724388 | 0.83 | PRKD1 (0.37) | JAK2JAK1JAK3IDO1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114341132-A | Substituted 1, 3-phenylheteroaryl derivatives and their use in the treatment of diseases | 诺华股份有限公司 | 2022-04-12 | — | — | CN | disclosed |