Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 5/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28724027 | 0.79 | MIF (0.40) | MIFTRPA1TRPV1 | |
| SCHEMBL27912769 | 0.72 | LMNA (0.52) | TRPA1ALDH1A1HPGD | |
| SCHEMBL8763446 | 0.72 | MIF (0.52) | MIFTRPA1TRPV1ALDH1A1CYP3A4 | |
| SCHEMBL28010163 | 0.72 | LMNA (0.52) | TRPA1ALDH1A1HPGD | |
| SCHEMBL28978740 | 0.71 | MAOB (0.33) | CYP3A4 | |
| SCHEMBL8762408 | 0.68 | MIF (0.52) | MIFTRPA1TRPV1ALDH1A1CYP3A4 | |
| SCHEMBL28724013 | 0.68 | MIF (0.31) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL29498932 | 0.67 | MIF (0.39) | MIFTRPA1TRPV1ALDH1A1CYP3A4 | |
| SCHEMBL29498912 | 0.67 | MIF (0.39) | MIFTRPA1TRPV1ALDH1A1CYP3A4 | |
| SCHEMBL8763223 | 0.66 | MIF (0.48) | MIFTRPA1TRPV1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114369097-B | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-114369097-A | Heteroaromatic AhR inhibitors | 山东轩竹医药科技有限公司 | 2022-04-19 | — | — | CN | disclosed |