Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972437 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2551777 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2516894 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2551776 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2512291 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL30429807 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL2512295 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL23358361 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL23358364 | 0.89 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL18973566 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107428792-B | Phosphoramides for the treatment of hepatitis B virus | 埃默里大学 | 2023-01-24 | — | — | CN | disclosed |