Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | LMNA | P02545 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2512291 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2516894 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2551776 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2551777 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2512295 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL17972437 | 1.00 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL17972438 | 0.94 | MAPT (0.50) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL28938599 | 0.90 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2510985 | 0.89 | MEN1 (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL2510987 | 0.89 | MEN1 (0.44) | ALDH1A1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595280-B2 | Phosphoramidates for the treatment of hepatitis B virus | EMORY UNIVERSITY (US) | 2026-04-07 | — | — | US | disclosed |
| US-20240309039-A1 | PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | EMORY UNIVERSITY | 2024-09-19 | — | — | US | disclosed |
| WO-2023044104-A1 | PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | EMORY UNIVERSITY (US) | 2023-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595280-B2 | Phosphoramidates for the treatment of hepatitis B virus | SLC10A1, BCL9L, OAT | ALDH1A1 3492/4885MAPT 3615/4885LMNA 2383/4885 |
| US-20240309039-A1 | PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | TYMP, PNP, MTAP | ALDH1A1 3093/4885MAPT 1611/4885LMNA 2289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.