Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31385458 | 0.82 | DGAT1 (0.40) | DGAT1 | |
| SCHEMBL21751633 | 0.80 | DGAT1 (0.37) | DGAT1KLKB1 | |
| SCHEMBL21751555 | 0.79 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751490 | 0.78 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751689 | 0.76 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL30074963 | 0.76 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL25349464 | 0.76 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751562 | 0.75 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL20767549 | 0.75 | DGAT1 (0.46) | DGAT1 | |
| SCHEMBL21751919 | 0.75 | DGAT1 (0.34) | DGAT1KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116270660-A | Bcl-2/Bcl-xl inhibitor-containing composition and preparation method and application thereof | 广州麓鹏制药有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116236583-A | Bcl-2/Bcl-xl inhibitor-containing composition and preparation method and application thereof | 广州麓鹏制药有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-115484933-A | Hot melt extrusion solid dispersions containing BCL2 inhibitors | 广州麓鹏制药有限公司 | 2022-12-16 | — | — | CN | disclosed |