Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767621 | 0.89 | AAK1 (0.33) | DGAT1MAPTALDH1A1HPGD | |
| SCHEMBL28435579 | 0.87 | DGAT1 (0.35) | DGAT1KLKB1 | |
| SCHEMBL20767572 | 0.82 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL28444204 | 0.82 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL21751870 | 0.80 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL28440805 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25615934 | 0.79 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL21751562 | 0.79 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751510 | 0.79 | MTNR1A (0.37) | DGAT1 | |
| SCHEMBL21751511 | 0.79 | MTNR1A (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115484933-A | Hot melt extrusion solid dispersions containing BCL2 inhibitors | 广州麓鹏制药有限公司 | 2022-12-16 | — | — | CN | disclosed |
| WO-2020041405-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |