Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
| ▸ | KDM5C | P41229 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 2/20 | 0.34 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 4/20 | 0.32 |
| ▸ | SGK1 | O00141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576299 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1ALOX15BRAFAXL | |
| SCHEMBL28736697 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1ALOX15BRAFAXL | |
| SCHEMBL17514144 | 0.79 | KDM4E (0.42) | HCAR3KDM4EALDH1A1NAPRTALOX15 | |
| SCHEMBL28736663 | 0.78 | ALDH1A1 (0.36) | HCAR2KDM4EALDH1A1NAPRTHSD17B10 | |
| SCHEMBL1145007 | 0.78 | HCAR3 (0.41) | HCAR2HCAR3KDM4EALDH1A1NAPRT | |
| SCHEMBL28586933 | 0.78 | HCAR2 (0.41) | HCAR2HCAR3KDM4EALDH1A1NAPRT | |
| SCHEMBL30692607 | 0.78 | HCAR3 (0.41) | HCAR2HCAR3KDM4EALDH1A1NAPRT | |
| SCHEMBL23107943 | 0.76 | RET (0.31) | — | |
| SCHEMBL4033925 | 0.76 | DYRK1B (0.42) | KDM4EALDH1A1DYRK1BMAPT | |
| SCHEMBL29935923 | 0.76 | PADI4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651810-A | Synthetic method of 3-formyl-1H-pyrazolo [3,4-b ] pyridine-5-carboxylic acid methyl ester | 上海毕得医药科技股份有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-113651810-B | Synthesis method of 3-formyl-1H-pyrazolo [3,4-b ] pyridine-5-carboxylic acid methyl ester | 上海毕得医药科技股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113651810-A | Synthetic method of 3-formyl-1H-pyrazolo [3,4-b ] pyridine-5-carboxylic acid methyl ester | 上海毕得医药科技股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651810-A | Synthetic method of 3-formyl-1H-pyrazolo [3,4-b ] pyridine-5-carboxylic acid methyl ester | 上海毕得医药科技股份有限公司 | 2021-11-16 | — | — | CN | disclosed |