SCHEMBL2894014

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2896546	0.81	LMNA (0.41)	LMNATDP1ALDH1A1KMT2AHPGD
	SCHEMBL2895355	0.79	USP2 (0.42)	LMNATDP1ALDH1A1ALOX15KMT2A
	SCHEMBL21362090	0.78	LMNA (0.42)	LMNATDP1ALDH1A1KMT2AHPGD
	SCHEMBL14870378	0.75	EGFR (0.42)	LMNATDP1ALDH1A1KMT2AUSP2
	SCHEMBL17718345	0.75	EGFR (0.42)	LMNATDP1ALDH1A1KMT2AUSP2
	SCHEMBL23212686	0.74	LMNA (0.43)	LMNATDP1ALDH1A1ALOX15KMT2A
	SCHEMBL30762112	0.74	LMNA (0.43)	LMNATDP1ALDH1A1ALOX15KMT2A
	SCHEMBL21362091	0.72	USP2 (0.41)	LMNATDP1ALDH1A1KMT2ANPSR1
	SCHEMBL4173841	0.72	KMT2A (0.38)	LMNATDP1KMT2AUSP2TSHR
	SCHEMBL4173838	0.72	KMT2A (0.38)	LMNATDP1KMT2AUSP2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.