Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28940249 | 1.00 | ADRB3 (0.44) | ADRB3ACACBADRB2ADRB1KDM4E | |
| SCHEMBL28737970 | 0.87 | PRMT5 (0.46) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL28737737 | 0.87 | PRMT5 (0.46) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL28737736 | 0.87 | PRMT5 (0.46) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL28478073 | 0.86 | CA2 (0.51) | ADRB2ADRB1KDM4E | |
| SCHEMBL28478074 | 0.86 | CA2 (0.51) | ADRB2ADRB1KDM4E | |
| SCHEMBL28472204 | 0.85 | KMT2A (0.44) | ADRB3ACACBADRB2ADRB1KDM4E | |
| SCHEMBL28737883 | 0.85 | ADRB2 (0.45) | ADRB3ADRB2ADRB1KDM4EALDH1A1 | |
| SCHEMBL28472202 | 0.85 | KMT2A (0.44) | ADRB3ACACBADRB2ADRB1KDM4E | |
| SCHEMBL28737882 | 0.85 | ADRB2 (0.45) | ADRB3ADRB2ADRB1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563103-B | Modulators of beta-3 adrenergic receptors for the treatment or prevention of disorders related thereto | 艾尼纳制药公司 | 2022-05-27 | — | — | CN | disclosed |