Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24343796 | 0.84 | ALDH1A1 (0.48) | LOXAOC3ALDH1A1RECQLMKNK2 | |
| SCHEMBL9572445 | 0.84 | KMT2A (0.58) | MEN1KMT2AMKNK1MKNK2 | |
| SCHEMBL16554530 | 0.81 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL9448404 | 0.80 | SIRT2 (0.49) | CHEK2MKNK1MKNK2 | |
| SCHEMBL21459847 | 0.76 | MEN1 (0.37) | MEN1KMT2ALOXAOC3ALDH1A1 | |
| SCHEMBL28292736 | 0.76 | KMT2A (0.41) | MEN1KMT2AMKNK1MKNK2CYP11B2 | |
| SCHEMBL28938407 | 0.75 | MKNK2 (0.53) | MEN1KMT2AMKNK1MKNK2CYP11B2 | |
| SCHEMBL4313658 | 0.75 | CYP11B1 (0.46) | ALDH1A1RECQLGCKCYP11B2CHRNB2 | |
| SCHEMBL24343865 | 0.73 | APP (0.45) | MEN1KMT2AALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL28940984 | 0.73 | APLNR (0.46) | MEN1KMT2AGAAMKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |