Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL27608132 | 1.00 | CA1 (0.50) | — | |
| Guanidine SCHEMBL23069845 | 1.00 | CA1 (0.50) | — | |
| Guanidine SCHEMBL28279993 | 1.00 | CA1 (0.50) | — | |
| Guanidine SCHEMBL2929472 | 1.00 | CA1 (0.50) | — | |
| Guanidine SCHEMBL6364290 | 0.96 | — | — | |
| Guanidine SCHEMBL6471890 | 0.96 | — | — | |
| Guanidine SCHEMBL21001927 | 0.96 | — | — | |
| Guanidine SCHEMBL392029 | 0.96 | CA1 (0.46) | — | |
| Guanidine SCHEMBL3669881 | 0.96 | — | — | |
| Guanidine SCHEMBL8647467 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 27866 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139329-A1 | METHOD TO CHARACTERIZE NUCLEIC ACID | ICHORtec GmbH (DE) | 2026-05-21 | — | — | US | claimed |
| EP-4743586-A1 | DETECTION METHOD FOR MYCOBACTERIA | The Royal Veterinary College (GB) | 2026-05-20 | — | — | EP | claimed |
| WO-2026098335-A1 | SOLAR CELL AND PREPARATION METHOD THEREFOR, AND PHOTOVOLTAIC ASSEMBLY, POWER GENERATION APPARATUS AND ELECTRIC APPARATUS | 宁德时代新能源科技股份有限公司 | 2026-05-15 | — | — | WO | claimed |
| EP-4741405-A1 | ENHANCED PEROVSKITE MATERIALS FOR PHOTOVOLTAIC DEVICES | CubicPV Inc. (US) | 2026-05-13 | — | — | EP | claimed |
| EP-4739727-A1 | CURING AGENT COMPOSITION COMPRISING SALTS OF THIOCYANATE | Hilti Aktiengesellschaft (LI) | 2026-05-13 | — | — | EP | claimed |
| CN-122017229-A | Colloidal gold immunochromatography test strip for saliva sample detection and preparation method thereof | 芯孚医疗科技(杭州)有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12617824-B2 | Silk protein coatings | AMSILK GMBH (DE) | 2026-05-05 | — | — | US | claimed |
| US-12617724-B2 | Hydraulic binder composition comprising blast furnace slag | STARCIN HOLDING FRANCE (FR) | 2026-05-05 | — | — | US | claimed |
| US-12618114-B2 | Method for identifying cancer in a subject | 23IKIGAI PTE LTD (SG) | 2026-05-05 | — | — | US | claimed |
| EP-4731596-A1 | NITROGEN STABILIZER COMPOSITIONS AND RELATED METHODS | Verdesian Life Sciences U.S., LLC (US) | 2026-04-29 | — | — | EP | claimed |
| WO-1987006621-A1 | CHAOTROPIC METHOD FOR EVALUATING NUCLEIC ACIDS IN A BIOLOGICAL SAMPLE | GILLESPIE DAVID | 1987-11-05 | — | — | WO | claimed |
| WO-1987005394-A1 | COMPETITIVE ELISA FOR THE DETECTION OF ANTIBODIES | UNITED STATES OF AMERICA, REPRESENTED BY THE UNITE (US) | 1987-09-11 | — | — | WO | claimed |
| EP-0234941-A2 | Competitive elisa for the detection of antibodies | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1987-09-02 | — | — | EP | claimed |
| US-4683293-A | GENETIC ENGINEERING, EXTRACTION, CHAOTROPHIC SALT | PHILLIPS PETROLEUM COMPANY (US) | 1987-07-28 | — | — | US | claimed |
| EP-0139878-A2 | Production of immune interferon and its mRNA | MELOY LABORATORIES, INC. (US) | 1985-05-08 | — | — | EP | claimed |
| US-4457372-A | INJECTING POLYSACCHARIDE AND WATER SOLUBLE GUANIDINE COMPOUND | TEXACO INC. (US) | 1984-07-03 | — | — | US | claimed |
| US-4440859-A | Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1984-04-03 | — | — | US | claimed |
| US-4362531-A | Agglutination immunoassays carried out with agent to reduce non-specific interferences | TECHNICON INSTRUMENTS CORPORATION (US) | 1982-12-07 | — | — | US | claimed |
| EP-0063482-A2 | Production of immune interferon and its mRNA | MELOY LABORATORIES, INC. (US) | 1982-10-27 | — | — | EP | claimed |
| US-3943954-A | Pipeline transportation of viscous hydrocarbons | TEXACO INC. (US) | 1976-03-16 | — | — | US | claimed |