Guanidine

Guanidine

SCHEMBL6471890

Cl.N#CS.N=C(N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanidine SCHEMBL392029 1.00 CA1 (0.46)
Guanidine SCHEMBL3505806 0.96
Guanidine SCHEMBL8647467 0.96
Guanidine SCHEMBL393937 0.96
Guanidine SCHEMBL23069845 0.96 CA1 (0.50)
Guanidine SCHEMBL27608132 0.96 CA1 (0.50)
Guanidine SCHEMBL28279993 0.96 CA1 (0.50)
Guanidine SCHEMBL28942 0.96
Guanidine SCHEMBL2929472 0.96 CA1 (0.50)
Guanidine SCHEMBL6364290 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10036062-B2 Primer middle sequence interference PCR technology Beijing Tag-Array Molecular Test Co., Ltd. (CN) 2018-07-31 US disclosed
US-20160237472-A1 PRIMER MIDDLE SEQUENCE INTERFERENCE PCR TECHNOLOGY Beijing Tag-Array Molecular Test Co., Ltd. (CN) 2016-08-18 US disclosed
CN-1816624-B Rice transposon gene CHINA NAT RICE RES INST 2010-05-05 CN disclosed
US-20060212961-A1 Rice transposon gene JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2006-09-21 US disclosed
CN-1816624-A Rice transposon gene JAPAN SCIENCE & TECH CORP (JP) 2006-08-09 CN disclosed
EP-1652921-A1 RICE TRANSPOSON GENE Japan Science and Technology Corporation (JP) 2006-05-03 EP disclosed
US-20050271622-A1 Construct of tumor-selective recombinant adenovirus, method for preparing the same and use thereof SHENZHEN ALLUCKS BIOTECH CO., LTD. (CN) 2005-12-08 US disclosed
US-20050079158-A1 Construct of anti-cancer recombinant adenovirus, method for preparing the same and use thereof SHENZHEN ALLUCKS BIOTECH CO., LTD. (CN) 2005-04-14 US disclosed
US-20030162206-A1 Ceramide kinase and DNA encoding it SANKYO COMPANY, LIMITED (JP) 2003-08-28 US disclosed
EP-0198645-A1 Human pancreatic elastase SANKYO COMPANY LIMITED (JP) 1986-10-22 EP disclosed