Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL27608132 | 1.00 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL28942 | 1.00 | — | — | |
| Guanidine SCHEMBL23069845 | 1.00 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL28279993 | 1.00 | CA1 (0.50) | CA1CA2 | |
| Guanidine SCHEMBL6364290 | 0.96 | — | — | |
| Guanidine SCHEMBL6471890 | 0.96 | — | — | |
| Guanidine SCHEMBL21001927 | 0.96 | — | — | |
| Guanidine SCHEMBL392029 | 0.96 | CA1 (0.46) | CA1CA2 | |
| Guanidine SCHEMBL3669881 | 0.96 | — | — | |
| Guanidine SCHEMBL8647467 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023218331-A1 | COMPOSITIONS AND METHODS FOR REMOVAL OF BOUND DETECTION AGENTS | VECTOR LABORATORIES, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| US-20230358649-A1 | COMPOSITIONS AND METHODS FOR REMOVAL OF BOUND DETECTION AGENTS | AUDAX PRIVATE DEBT LLC, AS AGENT | 2023-11-09 | — | — | US | disclosed |
| CN-108473983-A | Nucleic acid purification system using single wash and elution buffer | 皇家飞利浦有限公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-1234875-B1 | NOVEL METALLOPROTEASE HAVING AGGRECANASE ACTIVITY | ASTELLAS PHARMA INC (JP) | 2010-01-27 | — | — | EP | disclosed |
| EP-1602669-B1 | ANTIBODY AGAINST A TUMOR-SPECIFIC ANTIGEN AS TARGET | SANKYO CO (JP) | 2009-06-17 | — | — | EP | disclosed |
| EP-1602669-A1 | ANTIBODY AGAINST TUMOR SPECIFIC ANTIGEN AS TARGET | Sankyo Company Limited (JP) | 2005-12-07 | — | — | EP | disclosed |