Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28941989 | 0.86 | ALDH1A1 (0.51) | EGFRERBB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28941999 | 0.84 | NHERF1 (0.53) | EGFRERBB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28942009 | 0.84 | ALDH1A1 (0.52) | EGFRERBB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28942006 | 0.84 | POLB (0.48) | ALDH1A1SMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL28942000 | 0.84 | KMT2A (0.51) | EGFRERBB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL18516866 | 0.82 | ALDH1A1 (0.44) | EGFRERBB2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28941982 | 0.81 | KDM1A (0.44) | SMN1; SMN2L3MBTL1MMP2MMP1MMP9 | |
| SCHEMBL28941974 | 0.81 | KMT2A (0.53) | ALDH1A1SMN1; SMN2LMNAHPGDMMP2 | |
| SCHEMBL30363330 | 0.80 | GAA (0.55) | ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL28941980 | 0.80 | GAA (0.55) | ALDH1A1SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115650885-A | Preparation method of N-acyl-2-amino acrylate | 新乡学院 | 2023-01-31 | — | — | CN | disclosed |