Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | WNT3A | P56704 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.49 |
| ▸ | TUBB | P07437 | 1/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28658918 | 0.88 | NPC1 (0.64) | KMT2ALMNAALDH1A1HTTMEN1 | |
| SCHEMBL29236683 | 0.88 | LMNA (0.56) | KMT2ALMNAALDH1A1HTTMAPT | |
| SCHEMBL7823257 | 0.86 | ALDH1A1 (0.61) | KMT2ALMNAALDH1A1HTTMEN1 | |
| SCHEMBL29236768 | 0.84 | LMNA (0.68) | KMT2ALMNAALDH1A1HTTMAPT | |
| SCHEMBL29689390 | 0.84 | LMNA (0.68) | KMT2ALMNAALDH1A1HTTMAPT | |
| SCHEMBL28774662 | 0.84 | ALDH1A1 (0.50) | KMT2ALMNAALDH1A1HTTMAPT | |
| SCHEMBL28655358 | 0.82 | MAPT (0.56) | KMT2ALMNAALDH1A1HTTMAPT | |
| SCHEMBL30504084 | 0.82 | TUBB1 (0.67) | KMT2ALMNAHTTMAPTMEN1 | |
| SCHEMBL29066087 | 0.82 | TUBB1 (0.67) | KMT2ALMNAHTTMAPTMEN1 | |
| SCHEMBL30504071 | 0.82 | GAA (0.63) | KMT2ALMNAALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114573490-B | Diaryl-2H-aziridine compounds, preparation method and application thereof | 复旦大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-114573490-A | diaryl-2H-aziridines and diaryl aziridines compounds, preparation method and application thereof | 复旦大学 | 2022-06-03 | — | — | CN | disclosed |