Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185919 | 0.89 | RRM1 (0.53) | RRM1MAOBMEN1KMT2ALMNA | |
| SCHEMBL2809203 | 0.82 | MAOB (0.50) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL13433972 | 0.81 | MAOB (0.53) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL13131323 | 0.80 | MAOB (0.51) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL10922781 | 0.80 | MAOB (0.54) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL28944701 | 0.80 | MAOB (0.48) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL2805804 | 0.79 | MEN1 (0.52) | RRM1MAOBMEN1KMT2AKDM4E | |
| SCHEMBL27733470 | 0.77 | MAOB (0.58) | MAOBMEN1KMT2ASMN1; SMN2BCHE | |
| SCHEMBL3488958 | 0.77 | MEN1 (0.75) | MAOBMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11601970 | 0.76 | LMNA (0.69) | MAOBMEN1KMT2AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679324-B | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2012-10-03 | — | — | CN | disclosed |
| CN-101679324-A | Morpholine derivatives | MITSUBISHI TANABE PHARMA CORP | 2010-03-24 | — | — | CN | disclosed |