Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | DNM1L | O00429 | 4/20 | 0.39 |
| ▸ | CPT1A | P50416 | 2/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662148 | 0.90 | SCD (0.46) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL28785547 | 0.87 | CACNA1G (0.41) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL3751839 | 0.87 | SCD (0.44) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL3749747 | 0.84 | SCD (0.44) | SCDALDH1A1NPC1GAAMAPT | |
| SCHEMBL27797061 | 0.84 | GCK (0.42) | CACNA1GCACNA1HCACNA1IMAPT | |
| SCHEMBL28782750 | 0.82 | ALDH1A1 (0.46) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL3749465 | 0.81 | SCD (0.45) | SCDALDH1A1NPC1GAAMAPT | |
| SCHEMBL2657706 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1GAAMAPTRAB9A | |
| SCHEMBL3743722 | 0.80 | ALDH1A1 (0.43) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 | |
| SCHEMBL2660572 | 0.80 | CACNA1G (0.43) | SCDCACNA1GCACNA1HCACNA1IALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | claimed |
| CN-101679365-A | As the new pyrrole-2-carboxamides derivatives of glucokinase activators, their manufacture method and pharmaceutical application | ADVINUS THERAPEUTICS PRIVATE L | 2010-03-24 | — | — | CN | disclosed |