Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28792273 | 0.98 | BRD4 (0.36) | BRD4KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL8829299 | 0.75 | CYP3A4 (0.37) | KDM4EALDH1A1TSHRTDP1GAA | |
| SCHEMBL1424718 | 0.75 | PTGS2 (0.44) | KDM4EALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL16468077 | 0.71 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10GAAMAPT | |
| SCHEMBL8829243 | 0.69 | KDM4C (0.43) | KDM4EALDH1A1TDP1NAPRTGAA | |
| SCHEMBL3796726 | 0.68 | SIRT3 (0.44) | KDM4EALDH1A1TSHRTDP1MAPT | |
| SCHEMBL28826867 | 0.68 | KDM4E (0.42) | BRD4KDM4EALDH1A1TSHRTDP1 | |
| SCHEMBL24656778 | 0.67 | KDM5A (0.36) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL10953461 | 0.67 | TDP1 (0.47) | KDM4EALDH1A1TSHRTDP1ESR1 | |
| SCHEMBL20073402 | 0.66 | RAB9A (0.40) | KDM4EALDH1A1TSHRTDP1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104144930-A | New indolizine derivatives, method for preparing same and pharmaceutical compositions containing same | SERVIER LAB | 2014-11-12 | — | — | CN | disclosed |
| CN-102149714-A | Novel tricyclic derivatives, process for the preparation thereof and pharmaceutical compositions containing same | SERVIER LAB | 2011-08-10 | — | — | CN | disclosed |