SCHEMBL28945656

SCHEMBL28945656

COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)c1cnc(C(N)=O)cn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 2/20 0.41
HPGD P15428 2/20 0.41
RECQL P46063 1/20 0.41
CA2 P00918 1/20 0.39
CYP1A2 P05177 2/20 0.39
POLB P06746 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
DDB1 Q16531 1/20 0.39
CRBN Q96SW2 1/20 0.39
MAOB P27338 1/20 0.38
KMT2A Q03164 1/20 0.38
CCNC P24863 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30145626 0.93 SMN1; SMN2 (0.47) SMN1; SMN2ALDH1A1HPGDRECQLCYP1A2
SCHEMBL27730675 0.91 SIRT6 (0.51) SIRT6ALDH1A1HPGDRECQLCYP1A2
SCHEMBL28452713 0.88 SIRT6 (0.41) SIRT6SMN1; SMN2ALDH1A1HPGDRECQL
SCHEMBL28344438 0.88 SIRT6 (0.41) SIRT6SMN1; SMN2ALDH1A1HPGDRECQL
SCHEMBL7110573 0.84 HPGD (0.47) SMN1; SMN2ALDH1A1HPGDRECQLCYP1A2
SCHEMBL7105040 0.83 HPGD (0.54) SMN1; SMN2ALDH1A1HPGDRECQLCYP1A2
SCHEMBL7107993 0.80 SMN1; SMN2 (0.46) SMN1; SMN2ALDH1A1HPGDRECQLCYP1A2
SCHEMBL27730729 0.77 MAOB (0.61) SIRT6CA2CYP1A2NPC1RAB9A
SCHEMBL2482296 0.76 SIRT6 (0.45) SIRT6ALDH1A1HPGDCA2
SCHEMBL2516931 0.76 SIRT6 (0.45) SIRT6ALDH1A1HPGDCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115666371-A Sensor assembly with movable skin sensor 麦迪贝肯有限公司 2023-01-31 CN disclosed