Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | POLA1 | P09884 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 8/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 7/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30661721 | 0.83 | POLA1 (0.47) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL1398871 | 0.81 | ALDH1A1 (0.53) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL6027523 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL30514135 | 0.81 | ALDH1A1 (0.57) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL5138814 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL5440118 | 0.76 | CDK2 (0.49) | KDM4EALDH1A1CDK2CDK1CCNB1 | |
| SCHEMBL11077322 | 0.75 | ALDH1A1 (0.50) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| Octane SCHEMBL27777639 | 0.75 | POLA1 (0.46) | KDM4EALDH1A1POLA1CDK2CDK1 | |
| SCHEMBL7626879 | 0.75 | ALDH1A1 (0.46) | KDM4EALDH1A1POLA1CDK2RXFP1 | |
| SCHEMBL5482507 | 0.72 | ALDH1A1 (0.47) | KDM4EALDH1A1POLA1CDK2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4423288-A2 | COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY | GenVivo, Inc. (US) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023076180-A2 | COMPOSITIONS AND METHODS FOR THERAPEUTIC OR VACCINE DELIVERY | Genvivo, Inc. (US) | 2023-05-04 | — | — | WO | disclosed |
| EP-2152870-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | Sirna Therapeutics Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-2152878-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) | Sirna Therapeutics Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-2152875-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | Sirna Therapeutics Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-2152876-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | Sirna Therapeutics Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| EP-2152877-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE ( PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) | Sirna Therapeutics Inc. (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008137761-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | SIRNA THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137751-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | SIRNA THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137771-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE ( PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) | SIRNA THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137775-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) | SIRNA THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008137776-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF CYCLIC NUCLEOTIDE TYPE 4 PHOSPHODIESTERASE (PDE4B) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (SINA) | SIRNA THERAPEUTICS, INC. (US) | 2008-11-13 | — | — | WO | disclosed |
| EP-1987145-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS | Sirna Therapeutics Inc. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007076328-A2 | RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS | SIRNA THERAPEUTICS, INC. (US) | 2007-07-05 | — | — | WO | disclosed |