Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | GPR3 | P46089 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL714185 | 0.89 | LMNA (0.47) | LMNAHTTGPR3ESR1ESR2 | |
| SCHEMBL714184 | 0.79 | LMNA (0.45) | LMNAHTTGPR3ESR1ESR2 | |
| SCHEMBL65672 | 0.79 | CLK4 (0.50) | LMNAHTTADORA2AMAPTKDM4E | |
| SCHEMBL9910953 | 0.78 | LMNA (0.55) | LMNAHTTGPR3ADORA2ANUDT1 | |
| SCHEMBL971895 | 0.77 | LMNA (0.62) | LMNAHTTESR1ESR2ADORA2A | |
| SCHEMBL28239158 | 0.75 | LMNA (0.61) | LMNAHTTESR1ESR2ADORA2A | |
| SCHEMBL27810976 | 0.75 | LMNA (0.61) | LMNAHTTESR1ESR2ADORA2A | |
| SCHEMBL29514776 | 0.75 | ESR1 (0.73) | LMNAHTTESR1ESR2ADORA2A | |
| SCHEMBL194068 | 0.75 | ESR1 (0.73) | LMNAHTTESR1ESR2ADORA2A | |
| SCHEMBL4864061 | 0.74 | HTT (0.60) | LMNAHTTADORA2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461943-B | Copolymerized aryl ether sulfone containing bis-phthalazinone structure and preparation method thereof | 大连理工大学 | 2022-05-31 | — | — | CN | disclosed |