Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8308002 | 0.79 | KDM4E (0.56) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL38651627 | 0.77 | PKM (0.35) | KDM4EMAPTPOLB | |
| SCHEMBL11487909 | 0.75 | KDM4E (0.36) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL18603294 | 0.75 | KDM4E (0.43) | KDM4EMAPTALDH1A1POLB | |
| SCHEMBL21721500 | 0.65 | — | — | |
| SCHEMBL877015 | 0.63 | MAPT (0.64) | KDM4EMAPTALDH1A1POLB | |
| SCHEMBL24133585 | 0.62 | ALDH1A1 (0.46) | KDM4EMAPTALDH1A1HSD17B10 | |
| SCHEMBL20709970 | 0.62 | CSF1R (0.31) | KDM4EMAPTPOLB | |
| SCHEMBL21737391 | 0.61 | ADORA2A (0.31) | — | |
| SCHEMBL11478543 | 0.61 | KDM4E (0.39) | KDM4EMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667273-A | Competitive and non-competitive inhibitors of muscarinic acetylcholine receptor M5 | 范德堡大学 | 2023-01-31 | — | — | CN | disclosed |