Hydrazine

Hydrazine

SCHEMBL289463

CCOC(=O)C(=O)O.NN

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.50
ALDH1A1 P00352 7/20 0.48
EGLN1 Q9GZT9 1/20 0.46
LMNA P02545 1/20 0.46
HSD17B10 Q99714 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
GLO1 Q04760 1/20 0.44
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
SOAT1 P35610 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
CYP2D6 P10635 1/20 0.43
TSHR P16473 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
MAPT P10636 3/20 0.41
HPGD P15428 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL98770 0.94
SCHEMBL28119764 0.92
SCHEMBL28035895 0.92
Oxalic Acid SCHEMBL27581908 0.92 ALDH1A1 (0.50) ALOX15ALDH1A1EGLN1LMNAHSD17B10
Fluoride SCHEMBL27810482 0.92
Hydrochloric Acid SCHEMBL943803 0.92
SCHEMBL28863989 0.92
SCHEMBL27705013 0.92
SCHEMBL29240048 0.92
Ammonia Solution, Strong SCHEMBL27437639 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108746656-B Pre-alloyed powder for diamond products and preparation method thereof 威海职业学院 2021-11-26 CN claimed
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS INC (US) 2026-01-29 US disclosed
EP-4680608-A1 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS MMV Medicines for Malaria Venture (CH) 2026-01-21 EP disclosed
US-12465603-B2 Phthalazinone based modulators for the treatment of disease SOLEY THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
WO-2025077721-A1 MYT1 INHIBITOR BASED ON FUSED THIAZOLE OR PYRIDINE RING PHARMAENGINE, INC. (CN) 2025-04-17 WO disclosed
CN-114787155-B Pharmaceutical compounds 辉瑞公司 2025-02-28 CN disclosed
US-20240374589-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. 2024-11-14 US disclosed
WO-2024199260-A1 PYRAZOL-5-ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 南通泰禾化工股份有限公司 2024-10-03 WO disclosed
CN-118702628-A Pyrazole-5-ether compound as well as preparation method and application thereof 南通泰禾化工股份有限公司 2024-09-27 CN disclosed
EP-0995751-A2 Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction PFIZER INC. (US) 2000-04-26 EP disclosed
CN-1209129-A Antagonists of gonadotropin releasing hormone MERCK & CO LTD (US) 1999-02-24 CN disclosed
CN-1208412-A Gonadotropin releasing hormone antagonists MERCK & CO INC (US) 1999-02-17 CN disclosed
CN-1069271-A Preparation [1] chromene is the method for [4,3-c] pyrazole compound also BOOTS CO PLC (GB) 1993-02-24 CN disclosed
EP-0326873-A2 Teicoplanin hydrazides GRUPPO LEPETIT S.p.A. (IT) 1989-08-09 EP disclosed
US-4195087-A BACTERICIDES, FEED ADDITIVES ABIC, LTD. (IL) 1980-03-25 US disclosed
US-4075222-A VETERINARY MEDICINE, BACTERICIDES, FUNGICIDES, ANTIPROTOZOAN ELI LILLY AND COMPANY (US) 1978-02-21 US disclosed
US-4001230-A ANTIBACTERIAL, ANTIPROTAZOAL ELI LILLY AND COMPANY (US) 1977-01-04 US disclosed
US-3980794-A Method for promoting growth of poultry with 3-(5-nitro-2-imidazolyl)pyrazoles ELI LILLY AND COMPANY (US) 1976-09-14 US disclosed
US-3947467-A ANTIBACTERIAL, ANTIPROTOZOAL, ANTIFUNGAL ELI LILLY AND COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465603-B2 Phthalazinone based modulators for the treatment of disease MKI67, BCL2, CCAR2 ALOX15 1253/4885ALDH1A1 2021/4885EGLN1 1725/4885
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE NCOR1, NOP56, NCOR2 ALOX15 2235/4885ALDH1A1 2922/4885EGLN1 2988/4885
US-20240374589-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE MKI67, HDAC6, BCL2 ALOX15 1407/4885ALDH1A1 1827/4885EGLN1 2537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.