Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 9/20 | 0.40 |
| ▸ | NOS1 | P29475 | 8/20 | 0.40 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | NOS3 | P29474 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1269597 | 0.70 | KCNH2 (0.62) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL9877613 | 0.69 | KCNH2 (0.71) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL2936392 | 0.68 | KMT2A (0.46) | KCNH2 | |
| SCHEMBL4718869 | 0.68 | NOS1 (0.46) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL5747721 | 0.67 | KCNH2 (0.75) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL5748997 | 0.67 | KCNH2 (0.75) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL5746107 | 0.67 | KCNH2 (0.75) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL23989428 | 0.67 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL7795635 | 0.67 | NOS1 (0.46) | NOS2NOS1BACE1NOS3KCNH2 | |
| SCHEMBL8452074 | 0.67 | KMT2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805334-B | QC and GSK-3 beta multi-targeting inhibitor and preparation method and application thereof | 深圳大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114805334-A | QC and GSK-3 beta multi-target inhibitor and preparation method and application thereof | 深圳大学 | 2022-07-29 | — | — | CN | disclosed |