Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949211 | 0.79 | KMT2A (0.41) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL24076322 | 0.75 | MPO (0.40) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL3650533 | 0.75 | HCAR3 (0.44) | KDM4EKMT2AMEN1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL30168555 | 0.74 | MPO (0.39) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL25746400 | 0.73 | MPO (0.41) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL31366245 | 0.72 | MPO (0.40) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL24076248 | 0.72 | KDM4E (0.44) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL24246975 | 0.71 | MPO (0.39) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL24077090 | 0.70 | MPO (0.38) | KDM4EKMT2AMEN1PTGS2ALDH1A1 | |
| SCHEMBL24077086 | 0.67 | KDM4E (0.39) | KDM4EKMT2AMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |