⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27895792 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL4347152 | 0.79 | — | — | |
| SCHEMBL2082784 | 0.77 | — | — | |
| SCHEMBL20897489 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2305326 | 0.77 | L3MBTL1 (0.39) | — | |
| SCHEMBL30642875 | 0.77 | — | — | |
| SCHEMBL1161332 | 0.77 | — | — | |
| SCHEMBL4353450 | 0.77 | — | — | |
| SCHEMBL4455152 | 0.77 | — | — | |
| SCHEMBL10945071 | 0.77 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440666-B2 | Pyridazinone compounds and P2X7 receptor inhibitors | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20100286390-A1 | PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS | NISSAN CHEMICAL INDUSTRIES LIMITED | 2010-11-11 | — | — | US | disclosed |
| EP-2203429-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS | Nissan Chemical Industries, Ltd. (JP) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009057827-A1 | PYRIDAZINONE DERIVATIVES AND USE THEREOF AS P2X7 RECEPTOR INHIBITORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-05-07 | — | — | WO | disclosed |
| EP-1427285-A1 | ANTHRANILAMIDE ARTHROPODICIDE TREATMENT | E. I. du Pont de Nemours and Company (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1416796-A1 | METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003024222-A1 | ANTHRANILAMIDE ARTHROPODICIDE TREATMENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |
| WO-2003015518-A1 | METHOD FOR CONTROLLING PARTICULAR INSECT PESTS BY APPLYING ANTHRANILAMIDE COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |