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Formamide

Formamide

SCHEMBL28947237

CC1(C)CC=C(B2OC(C)(C)C(C)(C)O2)CC1.NC=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ P2RX7 Q99572 1/20 0.47
▸ MAPK1 P28482 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701389 0.90 P2RX7 (0.56) P2RX7MAPK1
SCHEMBL15181812 0.73 P2RX7 (0.53) P2RX7MAPK1
SCHEMBL20010552 0.73 P2RX7 (0.53) P2RX7MAPK1
SCHEMBL15181878 0.73 P2RX7 (0.53) P2RX7MAPK1
SCHEMBL662074 0.73 P2RX7 (0.53) P2RX7MAPK1
SCHEMBL12381903 0.73 P2RX7 (0.58) P2RX7MAPK1
SCHEMBL22079854 0.73 P2RX7 (0.42) P2RX7MAPK1
SCHEMBL23873562 0.72 P2RX7 (0.51) P2RX7MAPK1
SCHEMBL17256462 0.72 P2RX7 (0.50) P2RX7MAPK1
SCHEMBL15635589 0.71 P2RX7 (0.50) P2RX7MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115697994-A Fused quinazoline derivative, preparation method and medical application thereof 江苏恒瑞医药股份有限公司 2023-02-03 — — CN disclosed