SCHEMBL28947692

SCHEMBL28947692

C(=Cc1ccccc1N(C(=Cc1ccccc1)c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 4/20 0.44
TRPA1 O75762 2/20 0.41
NFE2L2 Q16236 2/20 0.38
SNCA P37840 2/20 0.36
MAPT P10636 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RELA Q04206 1/20 0.34
PTPN1 P18031 1/20 0.34
AKR1C1 Q04828 1/20 0.33
PLIN1 O60240 1/20 0.33
LMNA P02545 1/20 0.33
BCHE P06276 1/20 0.33
TNFRSF1A P19438 1/20 0.33
ACHE P22303 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6031703 0.81 TRPM8 (0.48) TRPM8MAPTMEN1ALDH1A1GAA
SCHEMBL9446229 0.81 TRPM8 (0.48) TRPM8MAPTMEN1ALDH1A1GAA
SCHEMBL9446234 0.81 TRPM8 (0.48) TRPM8MAPTMEN1ALDH1A1GAA
SCHEMBL38663472 0.79 TRPM8 (0.43) TRPM8TRPA1NFE2L2SNCAMAPT
SCHEMBL28185070 0.79 TRPM8 (0.43) TRPM8TRPA1NFE2L2SNCAMAPT
SCHEMBL2299170 0.77 TRPM8 (0.48) TRPM8MAPTMEN1ALDH1A1GAA
SCHEMBL8518680 0.76 TRPM8 (0.50) TRPM8TRPA1NFE2L2SNCAMAPT
SCHEMBL7005231 0.73 TRPM8 (0.44) TRPM8MAPTMEN1ALDH1A1GAA
SCHEMBL6405637 0.72 NFE2L2 (0.48) TRPM8TRPA1NFE2L2MEN1KMT2A
SCHEMBL1861624 0.72 NFE2L2 (0.48) TRPM8TRPA1NFE2L2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114746402-A Compound, organic thin-film light-emitting element, display device, and lighting device 东丽株式会社 2022-07-12 CN disclosed