Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 2/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.44 |
| ▸ | ASPH | Q12797 | 2/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21749959 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAKDM6B | |
| SCHEMBL28876515 | 0.87 | KDM4E (0.50) | NAPRTKDM4EALDH1A1GLAGAA | |
| SCHEMBL27648146 | 0.83 | NAPRT (0.44) | NAPRTKDM4EALDH1A1GLAGAA | |
| SCHEMBL19857454 | 0.82 | NAPRT (0.57) | NAPRTKDM4EALDH1A1KDM6BKDM4C | |
| SCHEMBL27727269 | 0.81 | ATR (0.51) | KDM4EALDH1A1GLAGAAKDM6B | |
| SCHEMBL27610033 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1GLAGAAKDM6B | |
| SCHEMBL20520322 | 0.81 | NAPRT (0.52) | NAPRTKDM4EALDH1A1KDM6BKDM4C | |
| SCHEMBL31043221 | 0.80 | ATR (0.49) | KDM4EALDH1A1GLAGAAKDM6B | |
| SCHEMBL28128057 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1GLAGAAKDM6B | |
| SCHEMBL2014671 | 0.79 | NOS2 (0.47) | KDM4EALDH1A1GLAGAAKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110291065-B | Novel isoindoline derivative, pharmaceutical composition and application thereof | 康朴生物医药技术（上海）有限公司 | 2022-08-19 | — | — | CN | disclosed |