Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23992857 | 0.78 | KMT2A (0.48) | MEN1MAPTKMT2AMCOLN3HTT | |
| SCHEMBL7004173 | 0.73 | DRD2 (0.47) | POLBDRD2DRD4DRD3HTR1A | |
| SCHEMBL1543001 | 0.71 | DRD2 (0.51) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL29277966 | 0.71 | DRD2 (0.51) | MAPTDRD2DRD4DRD3HTR1A | |
| SCHEMBL18074739 | 0.69 | DRD2 (0.49) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL18074770 | 0.69 | DRD2 (0.49) | DRD2DRD4DRD3HTR1AADRA1D | |
| SCHEMBL17328314 | 0.69 | DRD2 (0.49) | MEN1KMT2ADRD2DRD4DRD3 | |
| SCHEMBL3085048 | 0.68 | KMT2A (0.71) | MEN1MAPTKMT2AMCOLN3HTT | |
| SCHEMBL17646029 | 0.66 | HTR6 (0.42) | KMT2AHTTTDP1ALDH1A1L3MBTL1 | |
| SCHEMBL17856991 | 0.66 | DRD2 (0.43) | MAPTDRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698009-A | CD73 inhibiting 2,4-dioxopyrimidine compounds | 吉利德科学公司 | 2023-02-03 | — | — | CN | disclosed |