Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.50 |
| ▸ | F13A1 | P00488 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | TGM1 | P22735 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984560 | 0.84 | GPR119 (0.41) | GPR119F13A1TGM2TGM1NPC1 | |
| SCHEMBL27984923 | 0.83 | GPR119 (0.41) | GPR119F13A1TGM2TGM1JAK2 | |
| SCHEMBL27587919 | 0.81 | NPC1 (0.56) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27572305 | 0.81 | MMP13 (0.51) | GPR119F13A1TGM2TGM1NPC1 | |
| SCHEMBL27587914 | 0.81 | NPC1 (0.45) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL28750646 | 0.79 | GPR119 (0.50) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27587902 | 0.79 | MMP13 (0.48) | GPR119NPC1ALDH1A1MAPTMAPK1 | |
| SCHEMBL16820355 | 0.79 | GPR119 (0.56) | GPR119STS | |
| SCHEMBL12489357 | 0.74 | GPR119 (0.60) | GPR119JAK2JAK1 | |
| SCHEMBL29980570 | 0.74 | GPR119 (0.60) | GPR119JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104507936-A | Pyridinyl and pyrimidinyl sulfoxide and sulfone derivatives | FORMA TM LLC | 2015-04-08 | — | — | CN | disclosed |