Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948364 | 0.94 | PI4KA (0.32) | PI4KAPI4K2BPI4K2API4KBSIGMAR1 | |
| SCHEMBL28948262 | 0.88 | PI4KA (0.35) | PI4KAPI4K2BPI4K2API4KBSIGMAR1 | |
| SCHEMBL23161483 | 0.77 | PI4KA (0.38) | PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20609433 | 0.76 | HTR2C (0.33) | PI4KAPI4K2BPI4K2API4KBHTR2A | |
| SCHEMBL28948276 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL11501250 | 0.75 | ADORA2B (0.33) | — | |
| SCHEMBL18522458 | 0.74 | HTR2C (0.33) | HTR2AHTR2CHTR2B | |
| SCHEMBL11517457 | 0.73 | HTR2C (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL28948229 | 0.73 | HTR2C (0.46) | HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1995042 | 0.71 | HTR2C (0.33) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677729-A | AAK1 inhibitors | 武汉人福创新药物研发中心有限公司 | 2023-02-03 | — | — | CN | disclosed |