Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106511 | 0.89 | NLRP3 (0.44) | ACHENLRP3ESR1HIF1AELANE | |
| SCHEMBL12475116 | 0.86 | ACHE (0.40) | ACHEESR1HIF1AELANERECQL | |
| SCHEMBL5285423 | 0.85 | ACHE (0.49) | ACHEESR1HIF1AELANERECQL | |
| SCHEMBL4801387 | 0.83 | NLRP3 (0.50) | ACHENLRP3KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15548141 | 0.83 | KDM4E (0.41) | ACHENLRP3ESR1HIF1AALDH1A1 | |
| SCHEMBL7390544 | 0.79 | SMN1; SMN2 (0.50) | ACHEESR1HIF1AELANERECQL | |
| SCHEMBL2671806 | 0.79 | ACHE (0.47) | ACHEESR1HIF1AELANECA2 | |
| SCHEMBL7390463 | 0.79 | ACHE (0.44) | ACHENLRP3ESR1HIF1AELANE | |
| SCHEMBL7387661 | 0.78 | ACHE (0.43) | ACHEESR1HIF1AELANERECQL | |
| SCHEMBL7389800 | 0.78 | ACHE (0.43) | ACHENLRP3ESR1HIF1AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677831-A | Peptidomimetic STAT degradation drug, composition and application | 杭州和正医药有限公司 | 2023-02-03 | — | — | CN | disclosed |