Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28726978 | 0.84 | TRPM8 (0.40) | TRPM8TSPOCA12CA9NPC1 | |
| SCHEMBL28948542 | 0.83 | TSHR (0.40) | ALDH1A1GLAHTTLMNAMEN1 | |
| SCHEMBL28850407 | 0.82 | HPGD (0.46) | TRPM8TSPOCA12CA9NPC1 | |
| SCHEMBL28078011 | 0.80 | NPC1 (0.56) | TRPM8TSPONPC1RAB9AALDH1A1 | |
| SCHEMBL28995164 | 0.78 | TRPM8 (0.50) | TRPM8TSPONPC1RAB9AALDH1A1 | |
| SCHEMBL29009673 | 0.78 | POLB (0.56) | TRPM8TSPOCA12CA9NPC1 | |
| SCHEMBL29009677 | 0.75 | POLB (0.44) | TRPM8TSPOCA12CA9NPC1 | |
| SCHEMBL28499158 | 0.74 | GAA (0.36) | TSPOCA12CA9ALDH1A1SMN1; SMN2 | |
| SCHEMBL29009671 | 0.74 | POLB (0.43) | TRPM8TSPOCA12CA9NPC1 | |
| SCHEMBL30758070 | 0.74 | AKT1 (0.47) | TRPM8CA12CA9L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | claimed |
| CN-118908943-A | Preparation method of indolone-substituted isocoumarin compound | 内蒙古大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-116969875-A | Synthesis method of thioester functionalized 2-oxoindole | 南通大学 | 2023-10-31 | — | — | CN | disclosed |
| CN-115650980-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2023-01-31 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-114105978-A | Oxindole compound and preparation method and application thereof | 江西师范大学 | 2022-03-01 | — | — | CN | disclosed |