Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009673 | 0.88 | POLB (0.56) | POLBTRPM8RIPK1CA12CA9 | |
| SCHEMBL29009671 | 0.84 | POLB (0.43) | POLBTRPM8RIPK1CA12CA9 | |
| SCHEMBL30758070 | 0.79 | AKT1 (0.47) | POLBTRPM8RIPK1CA12CA9 | |
| SCHEMBL29009684 | 0.76 | LMNA (0.65) | CYP2C19MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL28948520 | 0.75 | TRPM8 (0.44) | POLBTRPM8CA12CA9HTT | |
| SCHEMBL29009664 | 0.73 | NPSR1 (0.46) | TRPM8CA12CA9HTTTSPO | |
| SCHEMBL1951077 | 0.72 | CYP1A2 (0.43) | TRPM8CYP2C19HTTMEN1KMT2A | |
| SCHEMBL28726978 | 0.71 | TRPM8 (0.40) | TRPM8CA12CA9HTTTSPO | |
| SCHEMBL29009648 | 0.71 | KMT2A (0.44) | TRPM8CA12CA9CYP2C19MEN1 | |
| SCHEMBL12545455 | 0.69 | LMNA (0.39) | CYP2C19HTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |