SCHEMBL28948643

SCHEMBL28948643

C=CCS(=O)(=O)ONC(C)=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861471 0.83 TGFBR1 (0.33)
SCHEMBL15671389 0.82
SCHEMBL3812635 0.80 TSHR (0.37)
SCHEMBL9810 0.72 ALDH1A1 (0.32)
SCHEMBL11050871 0.71
SCHEMBL28177673 0.71 KDM4E (0.35)
SCHEMBL902837 0.69
SCHEMBL8694565 0.68 ALDH1A1 (0.32)
SCHEMBL4360937 0.68
SCHEMBL252695 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104619709-A Imidazopyridine derivatives as modulators of TNF activity UCB PHARMA SA 2015-05-13 CN disclosed