Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.59 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153375 | 1.00 | HPGDS (0.59) | HPGDSP4HTMHDAC1HDAC3HDAC4 | |
| SCHEMBL28948987 | 0.98 | HPGDS (0.59) | HPGDSP4HTMKMT2AMEN1EPHX2 | |
| SCHEMBL30153214 | 0.98 | HPGDS (0.59) | HPGDSP4HTMKMT2AMEN1EPHX2 | |
| SCHEMBL30153319 | 0.95 | HPGDS (0.62) | HPGDSP4HTMKMT2AMEN1GABRA5 | |
| SCHEMBL28948982 | 0.95 | HPGDS (0.62) | HPGDSP4HTMKMT2AMEN1GABRA5 | |
| SCHEMBL22150633 | 0.77 | KDM4E (0.45) | HDAC1EPHX2KDM4ETGM2 | |
| Hydrochloric Acid SCHEMBL31092651 | 0.75 | NPC1 (0.57) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL15748014 | 0.74 | HPGDS (0.60) | HPGDSP4HTMKMT2AMEN1GABRA5 | |
| SCHEMBL19888923 | 0.73 | LMNA (0.59) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8872720 | 0.72 | KDM4E (0.57) | HPGDSEPHX2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115531554-A | Synthetic lethal nano-drug combined carrier and application thereof in preparation of GBM targeted drugs | 河南大学 | 2022-12-30 | — | — | CN | claimed |
| CN-115531554-B | Synthetic lethal nano-drug combination carrier and application thereof in preparation of GBM targeted drugs | 河南大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-115531554-A | Synthetic lethal nano-drug combined carrier and application thereof in preparation of GBM targeted drugs | 河南大学 | 2022-12-30 | — | — | CN | disclosed |