SCHEMBL15514

SCHEMBL15514

CCOC(=O)C=Cc1ccc(C(C)C)cc1C(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.50
TTR P02766 1/20 0.46
DPP4 P27487 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
ESR1 P03372 1/20 0.45
CYP3A4 P08684 2/20 0.44
CCNC P24863 1/20 0.42
CDK8 P49336 1/20 0.42
MAOB P27338 1/20 0.42
FDPS P14324 1/20 0.40
P2RY12 Q9H244 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
MDM4 O15151 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL648606 1.00 TYR (0.50) TYRTTRDPP4CA12CA1
SCHEMBL7183094 0.90 TYR (0.48) TYRTTRDPP4CA12CA1
SCHEMBL29693828 0.90 TYR (0.48) TYRTTRDPP4CA12CA1
SCHEMBL14342903 0.90 TYR (0.48) TYRTTRDPP4CA12CA1
Ethyl Cinnamate SCHEMBL28948990 0.89 KDM4E (0.48) TYRTTRDPP4CA12CA1
Ethyl Cinnamate SCHEMBL28948991 0.89 KDM4E (0.48) TYRTTRDPP4CA12CA1
Isopropyl 3-(4-Isopropylphenyl)Acrylate SCHEMBL28558517 0.89 CA12 (0.48) TYRTTRDPP4CA12CA1
SCHEMBL645927 0.84 ALDH1A1 (0.48) TYRTTRCA12CA1CA2
SCHEMBL157462 0.84 ALDH1A1 (0.48) TYRTTRCA12CA1CA2
SCHEMBL29435132 0.84 ALDH1A1 (0.48) TYRTTRCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3345 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230055665-A1 DELIVERY CARRIER INTO CELL ITO, KABUSIKIKAISYA (JP) 2023-02-23 US claimed
US-20190299032-A1 Oil-In-Water Type Emulsion Cosmetic Composition SHISEIDO COMPANY, LTD. (JP) 2019-10-03 US claimed
US-20180056096-A1 Oil-In-Water Type Emulsion Cosmetic Composition SHISEIDO CO., LTD. (JP) 2018-03-01 US claimed
US-20160128944-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME VYOME THERAPEUTICS LIMITED (IN) 2016-05-12 US claimed
EP-3003031-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME Vyome Biosciences Pvt Ltd (IN) 2016-04-13 EP claimed
CN-105407718-A Coated particles and compositions comprising the same VYOME BIOSCIENCES 2016-03-16 CN claimed
WO-2014195872-A1 COATED PARTICLES AND COMPOSITIONS COMPRISING SAME VYOME BIOSCIENCES PVT. LTD. (IN) 2014-12-11 WO claimed
US-20130195779-A1 SUBSTANTIVE SUNSCREEN FORMULATION MARY KAY INC. (US) 2013-08-01 US claimed
US-20130164232-A1 SUBSTANTIVE SUNSCREEN FORMULATION MARY KAY INC. (US) 2013-06-27 US claimed
US-20130156711-A1 TOPICAL SKIN CARE FORMULATION MARY KAY INC. (US) 2013-06-20 US claimed
US-20110286946-A1 SUNSCREEN COMPOSITIONS CONTAINING HYDROLYZED JOJOBA ESTERS FOR IMPROVED WATER RESISTANCE INTERNATIONAL FLORA TECHNOLOGIES LTD. (US) 2011-11-24 US claimed
US-20100047185-A1 ACTVIE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2010-02-25 US claimed
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008083974-A1 ACTIVE SUBSTANCE COMBINATION ISDIN S.A. (ES) 2008-07-17 WO claimed
WO-2008067928-A1 UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE ISDIN S.A. (ES) 2008-06-12 WO claimed
US-20070253989-A1 Modified Powder and Cosmetic Composition Using the Same SHISEIDO CO., LTD. (JP) 2007-11-01 US claimed
US-20060073106-A1 Novel stabilized cinnamic ester sunscreen compositions DSM IP ASSETS B.V. (NL) 2006-04-06 US claimed
EP-1589940-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP Assets B.V. (NL) 2005-11-02 EP claimed
WO-2004069216-A1 NOVEL STABILIZED CINNAMIC ESTER SUNSCREEN COMPOSITIONS DSM IP ASSETS B.V. (CH) 2004-08-19 WO claimed
US-20020131939-A1 Hair protection compositions ROCHE VITAMINS INC. 2002-09-19 US claimed