Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 3/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28037230 | 0.77 | IMPDH2 (0.51) | SNCAIMPDH2 | |
| SCHEMBL28037391 | 0.72 | TLR8 (0.44) | TLR8TLR7SNCAPDE4BTAAR1 | |
| SCHEMBL30315840 | 0.71 | MAPT (0.50) | TLR8TLR7SNCAKDM4EMAPT | |
| SCHEMBL13834917 | 0.70 | LRRK2 (0.45) | CHUKLRRK2IMPDH2 | |
| SCHEMBL3512037 | 0.66 | TAAR1 (0.44) | SNCAKDM4EHPGDTAAR1 | |
| SCHEMBL12127758 | 0.65 | APP (0.54) | CHUKLRRK2HSP90AB1MAPTCDC7 | |
| SCHEMBL13835403 | 0.65 | CHUK (0.53) | CHUKLRRK2IMPDH2 | |
| SCHEMBL21274452 | 0.65 | LRRK2 (0.53) | CHUKLRRK2IMPDH2 | |
| SCHEMBL13834754 | 0.65 | LRRK2 (0.53) | CHUKLRRK2IKBKBIMPDH2PRMT5 | |
| SCHEMBL3827956 | 0.65 | LRRK2 (0.53) | CHUKLRRK2IKBKBIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026393-A | Cdk9 kinase inhibitors | ABBVIE INC | 2015-11-04 | — | — | CN | disclosed |