Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30316130 | 0.85 | CA5A (0.49) | MAPTCA5ATP53NPC1CYP1A2 | |
| SCHEMBL30315815 | 0.84 | CA5A (0.46) | MAPTCA5AMAPK1APPFEN1 | |
| SCHEMBL30315911 | 0.84 | KMT2A (0.50) | MAPTCA5ATHRBTP53CYP1A2 | |
| SCHEMBL30315790 | 0.84 | MAPK1 (0.50) | MAPTCA5ARXFP1MAPK1SMN1; SMN2 | |
| SCHEMBL30315846 | 0.84 | KIF11 (0.49) | CA5APARP14APPFEN1TLR8 | |
| SCHEMBL30315791 | 0.77 | CA5A (0.49) | MAPTCA5APARP14APPFEN1 | |
| SCHEMBL30316056 | 0.77 | CA5A (0.49) | MAPTCA5ATP53NPC1CASP1 | |
| SCHEMBL30315873 | 0.77 | MAPT (0.53) | MAPTCA5APARP14APPFEN1 | |
| SCHEMBL30315901 | 0.77 | CA5A (0.49) | MAPTCA5ARXFP1PARP14TP53 | |
| SCHEMBL30315954 | 0.76 | KIF11 (0.49) | MAPTCA5APARP14APPFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850270-A | Alpha-carboline compound or pharmaceutical composition thereof, and preparation method and application thereof | 潍坊医学院 | 2023-03-28 | — | — | CN | disclosed |