⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vuf-5296 SCHEMBL8846403 | 0.80 | — | — | |
| Vuf-5297 SCHEMBL7508989 | 0.80 | — | — | |
| Vuf-5296 SCHEMBL8846552 | 0.80 | — | — | |
| Vuf-5296 SCHEMBL6136537 | 0.80 | — | — | |
| Vuf-5296 SCHEMBL7784076 | 0.80 | — | — | |
| SCHEMBL9044336 | 0.74 | — | — | |
| SCHEMBL17604203 | 0.70 | HRH4 (0.36) | — | |
| SCHEMBL5827852 | 0.70 | — | — | |
| SCHEMBL232190 | 0.69 | — | — | |
| SCHEMBL18998725 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137391-A1 | Histamine H3 Agonist for use as Therapeutic Agent for a Lipid/Glucose Metabolic Disorder | MSD K.K. (JP) | 2010-06-03 | — | — | US | claimed |
| EP-1938838-A1 | HISTAMINE H3 AGONIST FOR USE AS THERAPEUTIC AGENT FOR LIPID/GLUCOSE METABOLIC DISORDER | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | claimed |
| US-20100137391-A1 | Histamine H3 Agonist for use as Therapeutic Agent for a Lipid/Glucose Metabolic Disorder | MSD K.K. (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-1938838-A1 | HISTAMINE H3 AGONIST FOR USE AS THERAPEUTIC AGENT FOR LIPID/GLUCOSE METABOLIC DISORDER | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |