Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 6/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014817 | 1.00 | NTRK1 (0.34) | NTRK1THRBALDH1A1GLP1RC5AR1 | |
| SCHEMBL31692362 | 0.95 | NTRK1 (0.35) | NTRK1THRBALDH1A1 | |
| SCHEMBL38651834 | 0.95 | NTRK1 (0.34) | NTRK1 | |
| SCHEMBL30944794 | 0.93 | NTRK1 (0.31) | NTRK1 | |
| SCHEMBL20015354 | 0.92 | NTRK1 (0.34) | NTRK1ALDH1A1C5AR1 | |
| SCHEMBL21183669 | 0.92 | NTRK1 (0.36) | NTRK1THRBALDH1A1 | |
| SCHEMBL31424290 | 0.90 | NTRK1 (0.31) | NTRK1 | |
| SCHEMBL31424422 | 0.90 | NTRK1 (0.31) | NTRK1 | |
| SCHEMBL25267995 | 0.90 | ALDH1A1 (0.35) | NTRK1ALDH1A1GLP1R | |
| SCHEMBL21175197 | 0.90 | ALDH1A1 (0.35) | NTRK1ALDH1A1GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698003-A | Heterocyclic GLP-1 agonists | 加舒布鲁姆生物公司 | 2023-02-03 | — | — | CN | disclosed |