SCHEMBL30944794

SCHEMBL30944794

COC(CNC(=O)Nc1c2c(nn1-c1cc(C)c(F)c(C)c1)CCN(C(=O)OC(C)(C)C)[C@H]2C)OC.C[C@H]1c2c(n[nH]c2N)CCN1C(=O)OC(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ NTRK1 P04629 1/20 0.31
▸ F11 P03951 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28952289 0.93 NTRK1 (0.34) NTRK1
SCHEMBL20014817 0.93 NTRK1 (0.34) NTRK1
SCHEMBL31692362 0.89 NTRK1 (0.35) NTRK1
SCHEMBL38651834 0.88 NTRK1 (0.34) NTRK1
SCHEMBL20015354 0.86 NTRK1 (0.34) NTRK1
SCHEMBL21183669 0.85 NTRK1 (0.36) NTRK1
SCHEMBL31424290 0.84 NTRK1 (0.31) NTRK1
SCHEMBL31424422 0.84 NTRK1 (0.31) NTRK1
SCHEMBL25267995 0.83 ALDH1A1 (0.35) NTRK1
SCHEMBL21175197 0.83 ALDH1A1 (0.35) NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638421-A1 PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR Eli Lilly and Company (US) 2025-10-29 — — EP disclosed
WO-2024137426-A1 PROCESS TO MAKE GLP1 RA AND INTERMEDIATES THEREFOR ELI LILLY AND COMPANY (US) 2024-06-27 — — WO disclosed
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