Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.74 |
| ▸ | MMP2 | P08253 | 6/20 | 0.74 |
| ▸ | MMP9 | P14780 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952457 | 1.00 | MMP1 (0.74) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL28952440 | 0.92 | MMP1 (0.69) | MMP1MMP2MMP9ALDH1A1FFAR1 | |
| SCHEMBL28952439 | 0.92 | MMP1 (0.69) | MMP1MMP2MMP9ALDH1A1FFAR1 | |
| SCHEMBL28891777 | 0.88 | ALDH1A1 (0.73) | MMP1MMP2MMP9ALDH1A1KDM4E | |
| SCHEMBL28891815 | 0.88 | MMP1 (0.75) | MMP1MMP2MMP9ALDH1A1FFAR1 | |
| SCHEMBL15970744 | 0.85 | MMP1 (1.00) | MMP1MMP2MMP9ALDH1A1NPSR1 | |
| SCHEMBL15970747 | 0.85 | MMP1 (1.00) | MMP1MMP2MMP9ALDH1A1NPSR1 | |
| N-Benzylcinnamamide SCHEMBL16644095 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9ALDH1A1MEN1 | |
| N-Benzylcinnamamide SCHEMBL28891771 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9ALDH1A1MEN1 | |
| N-Benzylcinnamamide SCHEMBL957076 | 0.83 | MMP1 (1.00) | MMP1MMP2MMP9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368263-B | Synthesis and pharmaceutical application of cinnamic acid amide derivative | 南开大学 | 2024-05-17 | — | — | CN | disclosed |
| CN-115368263-A | Synthesis of cinnamic acid amide derivative and pharmaceutical application thereof | 南开大学 | 2022-11-22 | — | — | CN | disclosed |