SCHEMBL2895277

SCHEMBL2895277

CC(=O)NC[C@H]1CN(c2cc(F)c(-c3ccc(-n4cnc(C=O)c4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.47
MAOB P27338 2/20 0.47
PTGS1 P23219 2/20 0.47
SDHA P31040 2/20 0.47
LMNA P02545 1/20 0.47
CALML3 P27482 1/20 0.47
ABCB11 O95342 1/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.40
F10 P00742 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2893835 0.92 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2893833 0.92 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2899803 0.90 MAOA (0.44) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2899805 0.90 MAOA (0.44) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2896889 0.88 MAOA (0.48) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2894571 0.88 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2899881 0.88 MAOA (0.49) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2897263 0.88 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2891893 0.87 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA
SCHEMBL2899693 0.87 MAOA (0.47) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
EP-1799677-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS Ranbaxy Laboratories Limited (IN) 2007-06-27 EP disclosed
WO-2006038100-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2006-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD MAOA 1717/4885MAOB 2038/4885PTGS1 3182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.