Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28839045 | 0.80 | FFAR4 (0.42) | ADORA2AADORA3ADORA2BFFAR4KDM4E | |
| SCHEMBL28838935 | 0.80 | TYK2 (0.43) | TYK2ADORA2AADORA3ADORA2BLMNA | |
| SCHEMBL28838963 | 0.79 | ADORA3 (0.37) | ADORA2AADORA3ADORA2BBCL2L1MCL1 | |
| SCHEMBL23925790 | 0.78 | KDM1A (0.43) | KDM1ATGFBR1FYN | |
| SCHEMBL29740023 | 0.78 | KDM1A (0.43) | KDM1ATGFBR1FYN | |
| SCHEMBL26512732 | 0.76 | KDM1A (0.41) | KDM1AJAK1TYK2GRM5 | |
| SCHEMBL28838943 | 0.76 | ADORA3 (0.40) | TYK2ADORA2AADORA3ADORA2BLMNA | |
| SCHEMBL26120037 | 0.76 | TYK2 (0.43) | JAK1TYK2ADORA2AADORA3ADORA2B | |
| SCHEMBL28839054 | 0.75 | MAPT (0.40) | ADORA2AADORA3ADORA2BLMNAKDM4E | |
| SCHEMBL24497548 | 0.73 | METAP2 (0.51) | KDM1ALMNAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |