SCHEMBL28952946

SCHEMBL28952946

ClC(c1ccccc1)C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.48
DPP4 P27487 2/20 0.36
KCNN4 O15554 1/20 0.36
F2 P00734 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KCNA5 P22460 1/20 0.35
TRPA1 O75762 1/20 0.34
CYP1A2 P05177 1/20 0.34
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5459793 0.78 TSHR (0.46) TSHRDPP4KCNN4F2ALDH1A1
SCHEMBL21753496 0.76 TSHR (0.44) TSHRKCNN4ALDH1A1CNR1CNR2
SCHEMBL8525796 0.76 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL28497584 0.76 TSHR (0.48) TSHRKCNN4ALDH1A1CYP1A2TAAR1
SCHEMBL544573 0.74 TSHR (0.39) TSHRDPP4KCNN4F2ALDH1A1
SCHEMBL2789075 0.72 TSHR (0.50) TSHRDPP4F2HTR2ATAAR1
SCHEMBL1505841 0.72 TSHR (0.50) TSHRDPP4F2ALDH1A1HTR2A
SCHEMBL6741619 0.72 TAAR1 (0.41) DPP4KCNN4F2ALDH1A1CYP1A2
SCHEMBL10999597 0.70 TSHR (0.38) TSHRALDH1A1KCNA5CYP1A2CNR1
SCHEMBL28837273 0.70 SRC (0.39) TSHRDPP4KCNN4F2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677508-A Preparation method of glycol mononitrate 万华化学集团股份有限公司 2023-02-03 CN claimed
CN-115677508-A Preparation method of glycol mononitrate 万华化学集团股份有限公司 2023-02-03 CN disclosed